Most molecules contain different types of protons bonded hydrogens. However, when acting as acids, only the most acidic proton will participate in the acid-base reaction.
Therefore, it is important to be able to identify the most acidic proton in a molecule. There are three general methods to estimate the acidity of a proton:. Make sure that the proton in question is actually part of the functional group and is not simply attached to atoms that are attached to the functional group. Here is a short list of acidities of common functional groups in organic chemistry Note: that the pKa's are an approximate value for that functional group.
The most stable conjugate base will be the strongest acid. Method 1. Medication and Drugs. Study now. See Answer. Best Answer.
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Write your answer Related questions. In butane which hydrogen is more acidic hydrogen of ch3 or hydrogen of ch2 and why? Why are acids acidic? Do acidic solutions give some or many hydrogen ions? Which molecule is more reactive hydrogen or nitrogen? Does acidic solution have more hydrogen ions or hydroxide ions? What happens to the number of hydrogen ions if a solution becomes more acidic?
What can be deduced about the electronegativity of hydrogen relative to that of nitrogen? The lone pair electrons can be delocalized onto the adjacent carbonyl group to form a resonance-stabilized anion. Find most acidic hydrogen? Truong-Son N. Feb 6, Identify familiar functional groups. Ernest Z. The most acidic hydrogens are d p. Explanation: b Y Protons Y are alkane hydrogens.
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